➡️Join forces with someone who is already making a difference. ➡️Worry more about giving than receiving. The point of resistance is the point of greatest opportunity. Ways to make the most of opportunities 👇
The door of opportunity swings on unexpected hinges. #Macrocycles #DrugDiscovery #Innovation #Biotech #Therapeutics #ScientificRevolutionĮveryone who says, “I wish I had more opportunities,” doesn’t understand opportunities. 🤓💪💊💥Īt Arctoris, in partnership with companies like SpiroChem, and Cyclenium Pharma Inc., we can help you unlock your most challenging targets with the power of macrocycles! Join the revolution and unlock the secrets of these mesmerising molecules that hold the key to innovative therapeutics. 💥 Brace yourself for the future of drug discovery! Macrocycles are redefining the possibilities, blending scientific ingenuity with limitless potential. As a result, macrocycle-based drugs exhibit heightened selectivity, reducing the risk of adverse side effects and enhancing patient safety. With each modification and functionalisation, they unlock new realms of potential, paving the way for groundbreaking discoveries and optimising these wondrous molecules for remarkable drug-like properties.Ħ️⃣ Precision Strikes: Macrocycles hit their mark with impeccable accuracy! Their size and complexity allow for laser-focused targeting, minimising off-target effects. Researchers wield these powerful tools to create expansive libraries of awe-inspiring macrocycles. This superpower translates to less frequent dosing, granting patients the gift of convenience and improved compliance.ĥ️⃣ Infinity of Possibilities: Prepare to be captivated by the boundless chemical diversity within macrocycles.
Their larger size allows them to outmanoeuvre enzymatic degradation and navigate biological barriers effortlessly, ensuring optimal absorption and distribution throughout the body.Ĥ️⃣ Prolonged Power: Macrocycle superheroes are here for the long haul! Compared to their smaller counterparts, these mighty molecules exhibit longer half-lives and extended durations of action. These bRo5 molecular heroes are revolutionising the fight against diseases like cancer and viral infections by skilfully modulating disruptive PPIs, restoring harmony within our cells.ģ️⃣ Orally Impressive: No more swallowing large doses! Macrocycles flaunt superior oral bioavailability, making them true champions in drug delivery. With this structural diversity, macrocycles become a force to be reckoned with, displaying exquisite binding affinities and unrivalled selectivity, making them perfect for tackling specific disease-causing proteins head-on!Ģ️⃣ Breaking Barriers: Say goodbye to traditional limitations! Macrocycles have the power to target protein-protein interactions (PPIs) and other elusive biological targets, such as mRNA, that were once deemed untouchable. Their grand cyclic structures grants them remarkable rigidity and a three-dimensional nature, allowing them to interact with biological targets like never before. The next chapter in small molecule drug discovery? #macrocycles! Here's why:ġ️⃣ Shape-shifting Superstars: Macrocycles boast unique chemical properties that set them apart from conventional small molecules.
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